DISCOVER THE FUTURE

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Holy Shit Tech

A hard-to-treat colorectal tumor may lack a supply line, not soldiers: a Shenzhen, China team reports in Science that OX40 plus PD-1 rewired immunity in mice ↗

Lei Zhang’s group at Shenzhen Bay Laboratory reports in Science that PD-1–responsive colorectal tumors contain a spatial niche of helper T cells that arrive from lymph nodes. In mice, an OX40 agonist plus PD-1 blockade pushed that peripheral supply line and slowed tumor growth.

Big Moves

Musk: Future Starship Flights Will Carry Over 50 Tb/s of Starlink Bandwidth ↗

Elon Musk said on X on November 14 that future Starship flights will each carry over 50 Tb/s of Starlink bandwidth to orbit. Official Starlink figures put today’s Flight 15 load of 26 V3 satellites at up to 26 terabits of capacity, or about 26 Tbps at 1 Tbps per satellite. Musk’s target is roughly double that, or more than 50 V3-class satellites in one flight.